Agentic AI Platform for Hypothesis Generation in Biopharma R&D – PoC

What if scientific hypotheses could be generated not just faster—but with traceable logic, real-time citations, and domain-specific reasoning? A global biopharma company exploring AI’s role in early-stage R&D teamed up with Factspan to test this idea.
Executive Summary

What if scientific hypotheses could be generated not just faster—but with traceable logic, real-time citations, and domain-specific reasoning? A global biopharma company exploring AI’s role in early-stage R&D teamed up with Factspan to test this idea. The focus: apply Agentic AI to automate hypothesis generation for use cases like biomarker discovery and diagnostics.

Factspan designed a multi-agent prototype that orchestrated LLMs, integrated biomedical knowledge graphs, and produced audit-ready scientific outputs. Built for explainability and compliance, the early-stage platform showed how GenAI could complement human researchers in complex, high-stakes environments.

Business Impact:
  • ~60% reduction in literature review and drafting time
  • 3x faster creation of structured assay reports
  • Complete traceability of outputs via embedded logging
  • Significantly reduced review effort through integrated human validation

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